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Polymorphisms of the FcγRIIIa gene associated with high or low affinity for Ig Fc have been described that could influence the efficacy of rituximab binding affinity
Acts as a regulator of cellular senescence and cellular ploidy by mediating phosphorylation of 'Ser-464' of LATS1
altering the sensitivity of target tissues to leptin actions and producing a state called leptin resistance in analogy to in sulin resistance
and gamma have been identified
1× Working concentration not recommended for storage 10× Buffer for concentration and dilution 1 After opening
Alexa Fluor® 488 Mouse Anti-Human CD16a Antibody (S-564-39) Size:500T Polymorphisms of the FcγRIIIa geneProduct Specification Host Mouse Antigen CD16a Synonyms Low affinity immunoglobulin gamma Fc region receptor III A; IgG Fc receptor III A; CD16 II; CD16a antigen; Fc gamma RIII alpha; Fc gamma RIII; FcRIII; FcRIIIa; FcgammaRIIIA; FcR 10; IgG Fc receptor III 2; FCGR3A; FCG3; FCGR3; IGFR3 Immunogen Synthetic Peptide Location Secreted, Cell membrane Accession P08637 Clone Number S 564 39 Antibody Type Mouse mAb Isotype IgG1,k Application FCM Reactivity