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This binding contributes to TNF-alpha induced signaling
induces UCP2-dependent mitochondrial rewiring that attenuates the generation of reactive oxygen species and preserves the integrity of Krebs cycle required for persistent production of itaconate and subsequent GATA3-dependent differentiation of inflammation-resolving alternatively activated macrophages
application dilution species WB 1:1000 ICC 1:500 IP 1:50 IHC-P 1:2000 FCM 1:500
IL-35 secreted by regulatory T cells (Tregs) inhibits the inflammatory response of immune cells
Other OSM-mediated activities reported to date include: stimulation of plasminogen activator activity in cultured bovine aortic endothelial cells
ANDR(LBD) Protein, Human Molecular Biology Kits This binding contributes to TNF-alphaProduct Specification Species Human Synonyms DHTR, NR3C4, AR Accession P10275 1 Amino Acid Sequence D551 T919N terminal 8x His and SUMO tag, C terminal Myc tag Expression System E. coli Molecular Weight 56. 5 kDa Purity >75% by SDS PAGE Conjugation Unconjugated Tag His Tag, SUMO, Myc Physical Appearance Liquid Storage Buffer 25mM Hepes, 150 mM NaCl, 2 mM DTT, 10 M DHT, 5% glycerol, pH7. 5 Stability & Storage Stable for 12 months upon stored at 80 from