The use of IL-21 blocking mAb used in a xenogeneic mouse model (with NOD/SCID/γc−/- recipients) has demonstrated a decrease in CD8+ T cells and an increased proportion of Tregs
Genes Cancer
is a B cell restrictive glycoprotein that is expressed in the cytoplasm of progenitor B and pre-B cells and on the surface of mature B cells
Species Mouse Accession P35846 Amino Acid Sequence Thr25-Ser232
Human CD33 is expressed on the cell membrane as two isoforms
IL10RB His Tag Protein, Human Size:500μg The use of IL-21 blockingProduct Specification Species Human Synonyms CDw210B, CRF2 4, CRFB4, CRFB4, D21S58, D21S66, IBD25, IL 10R2 Accession Q08334 Amino Acid Sequence Met20 Ser220, with C terminal 8*His MVPPPENVRMNSVNFKNILQWESPAFAKGNLTFTAQYLSYRIFQDKCMNTTLTECDFSSLSKYGDHTLRVRAEFADEHSDWVNITFCPVDDTIIGPPGMQVEVLADSLHMRFLAPKIENEYETWTMKNVYNSWTYNVQYWKNGTDEKFQITPQYDFEVLRNLEPWTTYCVQVRGFLPDRNKAGEWSEPVCEQTTHDETVPSGGGSHHHHHHHH Expression System HEK293 Molecular Weight 33 50kDa Purity 95%